Personalized Brain-Body Healing Rooted in the BIG-E Connection
Functional Medicine That Targets the Root—Not Just the Symptoms
Dr. Anthony Serle specializes in functional medicine in Jacksonville and St. Augustine, with a unique focus on the Brain-Immune-Gut-Genetics-Endocrine (BIGGE) axis. By restoring balance across these vital systems, Dr. Serle helps uncover the why behind chronic conditions like anxiety, fatigue, brain fog, insomnia, diabetes, high cholesterol, hypothyroidism, autoimmune diseases, infections, hormonal imbalances, and digestive issues—so you can finally heal, not just cope.
Conditions
Looking for help with chronic symptoms in Jacksonville or St. Augustine?
Many symptoms share one thing in common: genetics, or an imbalance in the brain, gut, immune, or endocrine systems. Dr. Serle’s approach looks beyond the label—whether it’s anxiety, ADHD, or autoimmune issues—to uncover why you're experiencing your symptoms. Click below to learn how he treats each condition by addressing the root, not just the result.
Functional Medicine seeks to identify and address the root causes of disease.
There are over 80,000 synthetic chemicals in our environment. Many are used in everday items including foods, prescription drugs, beverages, hair and skin products.
Stresses of all kinds begin to take their toll on the body and eventually dysfunction results. If the stresses continue, this dysfunction leads to symptoms.
If we don’t heed the warning that the symptoms represent, we might allow a dysfunction to develop into a full-blown disease.
Now we can truly treat and cure disease with Functional Medicine, it is the future of conventional medicine. It views the body as one integrated system, not a collection of independent organs divided up by medical specialties.
All Your System Connected.
Dr. A. Serle believes that each individual is unique, with distinct genetic makeups, histories, and life experiences. Dr. Serle's mission is to uncover the root causes of your health concerns and provide a personalized plan tailored to your specific needs.
Brain-Immune-Gut-Genetics-Endocrine (BIGGE)
Dr. Serle's unique focus on the Brain-Immune-Gut-Genetics-Endocrine (BIGGE) axis has helped thousands of patients in the St. Augustine and Jacksonville areas. By restoring balance across these vital systems, Dr. Serle helps uncover the why behind chronic conditions like Anxiety, Depression, ADHD, Migraines, Autoimmune Disorders, Cardiovascular disease, Thyroidism, Irregular Hormones, Chronic Fatigue Syndrome, Fibromyalgia, Chronic Infections, and Digestive issues—so you can finally heal, not just cope.
Personalize Your Diet
There are so many diet books on the market that claim to help improve your health. Most of these diets will work for most people (70%) for a short term. But to truly achieve your health goals and sustain your health, you must “Personalize your Diet”
Meet Dr. Serle: A Journey Fueled by Science, Service, and a Deep Calling to Heal
Dr. Anthony Serle’s path to functional medicine didn’t begin in a lab—it began with a deep desire to truly help people who weren’t getting answers from conventional care. With over two decades of experience, he’s become a trusted voice in the field by blending clinical precision with personal dedication to whole-body healing. Discover the story behind the doctor who's changing lives through the BIG-E approach.
Convenient, Doctor-Recommended Supplements
Dr. Serle offers his patients exclusive access to high-quality supplements through trusted professional-grade dispensaries—delivered straight to your door. As a patient, you’ll receive a significant discount and guidance on exactly what your body needs.
The Clinic
At his welcoming clinic in Jacksonville, Florida, Dr. Anthony Serle offers personalized health solutions by analyzing the brain and all bodily systems. Conveniently located for residents of Jacksonville and nearby St. Augustine. Today, with over 30 years of combined experience in neurology, functional medicine, and hospital-based care, Dr. Serle's team offers a truly integrated approach—blending traditional medicine with advanced functional and alternative strategies to help patients achieve lasting wellness. You're ready to move beyond band-aid treatments and experience personalized care that addresses the root of your health challenges. We would be honored to walk that journey with you.
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Testimonials
Why Patients Trust Dr. Serle
With over 25 years of clinical experience, Dr. Anthony Serle is North Florida’s only doctor endorsed by both the Institute for Functional Medicine and Functional Medicine University. His integrative expertise and commitment to root-cause healing set him apart in the Jacksonville and St. Augustine communities.
Frequently Ask Questions
The BIGGE approach focuses on the interconnected systems of your Brain, Immune, Gut, Genetic, and Endocrine health. Instead of just treating symptoms, Dr. Serle looks for the root imbalance across these five systems—because real healing starts when we understand the “why” behind your condition..
Functional medicine can support a wide range of chronic issues including fatigue, anxiety, ADHD, digestive problems, autoimmunity, and hormone imbalances. By assessing your BIGGE systems, we can develop a personalized plan to rebalance your health and restore function.
The initial consultation costs $297, and the follow-up consultation costs $100. We do not take insurance.
When ordering blood work (if necessary), Dr. Serle utilizes lab companies (QuestDiagnostics and LabCorp) that accept all major health insurance plans, except for Medicare and Medicaid. For patients with Medicare or Medicaid insurance, the cash price for blood work will be between $250 and $450, depending on the health issues. This applies to patients who have no health insurance as well.
The brain map is also called quantitative electroencephalography (QEEG). Its analysis involves recording digital EEG signals, which are processed, transformed and analyzed using complex mathematical algorithms. The QEEG/Brain map is an extensive exam used at Harvard, UCLA, Utah, South Carolina, and Tennessee. It will provide a picture of the patient’s brain wave patterns and help Dr. Serle determine the areas of concern in the brain.
No, the Brain Map is Non-Invasive. There’s no current going into the brain. The brain map records electric impulses (brainwaves) just like an EKG records electrical impulses from the heart.
Dr. Serle does not treat children less than 16 years old.
Schedule a Consult
with Dr. Serle Today!
He’s helped thousands of people get to the root cause of their condition, eliminating symptoms, and reclaiming their vitality. It will take hard work and commitment but it will be well worth it to you and your family.