What is BiGGE?
The BiGGE Axis represents a revolutionary, integrative model of health that links the brain, immune system, gut microbiome, genetics, and endocrine (hormonal) function. At BiGGE, we see the body as a system — not a set of isolated parts.
What Is the
BiGGE Axis?
The BiGGE Axis is a comprehensive, systems biology approach to understanding the body’s complex communication networks. It emphasizes how seemingly separate physiological systems are deeply interrelated and mutually influential:
- Brain: Central to perception, emotion, and neurochemical signaling
- Immune: Regulates defense, inflammation, and repair processes
- Gut: Home to the microbiome, nutrient absorption, and neuroimmune signaling
- Genetics: Blueprint that influences all body systems and their interactions
- Endocrine: Hormonal system regulating metabolism, stress, and reproduction
This model helps clinicians, researchers, and patients view health through a more integrated and personalized lens.
Frequently Ask Questions
The BIGGE approach focuses on the interconnected systems of your Brain, Immune, Gut, Genetic, and Endocrine health. Instead of just treating symptoms, Dr. Serle looks for the root imbalance across these five systems—because real healing starts when we understand the “why” behind your condition..
Functional medicine can support a wide range of chronic issues including fatigue, anxiety, ADHD, digestive problems, autoimmunity, and hormone imbalances. By assessing your BIGGE systems, we can develop a personalized plan to rebalance your health and restore function.
The initial consultation costs $297, and the follow-up consultation costs $100. We do not take insurance.
When ordering blood work (if necessary), Dr. Serle utilizes lab companies (QuestDiagnostics and LabCorp) that accept all major health insurance plans, except for Medicare and Medicaid. For patients with Medicare or Medicaid insurance, the cash price for blood work will be between $250 and $450, depending on the health issues. This applies to patients who have no health insurance as well.
The brain map is also called quantitative electroencephalography (QEEG). Its analysis involves recording digital EEG signals, which are processed, transformed and analyzed using complex mathematical algorithms. The QEEG/Brain map is an extensive exam used at Harvard, UCLA, Utah, South Carolina, and Tennessee. It will provide a picture of the patient’s brain wave patterns and help Dr. Serle determine the areas of concern in the brain.
No, the Brain Map is Non-Invasive. There’s no current going into the brain. The brain map records electric impulses (brainwaves) just like an EKG records electrical impulses from the heart.
Dr. Serle does not treat children less than 16 years old.
Schedule a Consult
with Dr. Serle Today!
He’s helped thousands of people get to the root cause of their condition, eliminating symptoms, and reclaiming their vitality. It will take hard work and commitment but it will be well worth it to you and your family.